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In 24 healthy subjects, when prograf was administered 1.

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Shakingheadachediarrheanausea/vomitingupset stomachloss of appetitetrouble sleepingand tingling of the hands/feet may occurIf any of these effects persist or worsentell your doctor or pharmacist promptly.

Monitoring of tacrolimus blood concentrations in conjunction with other laboratory and clinical parameters is considered an essential aid to patient management for the evaluation of rejectiontoxicitydose adjustments and complianceObserved whole blood trough concentrations can be found in Table 1Factors influencing frequency of monitoring include but are not limited to hepatic or renal dysfunctionthe addition or discontinuation of potentially interacting drugs and the post-transplant timeBlood concentration monitoring is not a replacement for renal and liver function monitoring and tissue biopsiesData from clinical trials show that tacrolimus whole blood concentrations were most variable during the first week post-transplantation.

Prograf can harm your kidneysand this effect is increased when you also use certain other medicines harmful to the kidneysBefore using Prograftell your doctor about all other medicines you useMany other drugsincluding some over-the-counter medicinescan be harmful to the kidneys.

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